Searchable abstracts of presentations at key conferences in endocrinology

ea0002oc24 | Reproduction | SFE2001

THE ACTIVATION OF PERIPHERAL NEUROKININ RECEPTORS IN THE PATHOLOGY OF PRE-ECLAMPSIA

Bell N , Graham G , Gibbins J , Lowry P , Page N

Mild symptoms of pre-eclampsia (PE) include hypertension and proteinuria, but more severe cases develop cerebrovascular accident, liver capsule distention, platelet pathology, pulmonary oedema and renal failure. As we have recently reported neurokinin B (NKB) levels to be significantly raised in the plasma of women with PE, the aim of this study is to establish the pathological role of NKB in this disease.NKB acts predominantly through the NK3 receptor, ...